Fig. 4. hH3 and hH4 in the telomeric NCP fold into the same structures as in the Widom 601 NCP with a few minor local conformational differences.

a Overlay of the 2D NCA, b NCO, and c ¹³C–¹³C DARR SSNMR spectra of the Widom 601 NCP (red) and telomeric NCP (black) containing uniformly ¹³C, ¹⁵N-labeled hH3. d Overlay of the 2D NCA, e NCO, and f ¹³C–¹³C DARR SSNMR spectra of the Widom 601 NCP (red) and telomeric NCP (black) containing uniformly ¹³C, ¹⁵N-labeled hH4. DARR spectra were collected with 20 ms mixing time.