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. 2020 Oct 30;10:18729. doi: 10.1038/s41598-020-75290-4

Table 2.

Linear regression of PASP, entire cohort.

Variables β-estimate (mmHg)
[95% CI]*
p value
HIV/HCV status
Uninfected Ref
HIV mono-infected 0.002 [− 0.93, 0.93] 0.9963
HCV mono-infected 0.45 [− 0.66, 1.57] 0.4259
Co-infected 1.10 [0.01, 2.20] 0.0484
Age, 10 years 0.21 [− 0.22, 0.63] 0.3453
Race
White Ref
African American 2.02 [ 1.20, 2.85]  < .0001
Hispanic  − 3.31 [− 4.56, − 2.06]  < .0001
Other 0.16 [− 2.17, 2.49] 0.8953
Male Sex 7.40 [5.31, 9.50]  < .0001
BMI 0.04 [− 0.02, 0.10] 0.2436
Heart failure status
HF Preserved EF 7.83 [6.18, 9.48]  < .0001
HF with EF between 40 & 50 6.46 [4.00, 8.92]  < .0001
HF Reduced EF 5.78 [4.37, 7.18]  < .0001
No EF 7.94 [6.90, 8.98]  < .0001
No HF Ref
History of CHD 1.02 [0.24, 1.80] 0.0102
Hypertension
No Hypertension Ref
Controlled HTN 0.31 [− 1.27, 1.88] 0.7003
Uncontrolled HTN 1.65 [− 0.02, 3.31] 0.0523
COPD 1.96 [1.19, 2.72]  < .0001
Stroke History  − 1.19 [− 2.55, 0.16] 0.0844
Diabetes Mellitus 0.89 [0.13, 1.66] 0.0214
Dyslipidemia  − 0.44 [− 1.18, 0.30] 0.2480
Smoking status
Current 0.46 [− 0.50, 1.43] 0.3438
Former 0.91 [− 0.19, 2.02] 0.1049
Never Ref
Alcohol Use 0.21 [− 0.67, 1.09] 0.6346
Cocaine Use  − 1.53 [− 2.55, − 0.50] 0.0034
eGFR  − 0.03 [− 0.04, − 0.01]  < .0001
FIB-4 0.31 [0.17, 0.45]  < .0001
Hemoglobin  − 0.75 [− 0.94, − 0.56]  < .0001

PASP pulmonary arter systolic pressure, HCV hepatitis C virus, CI confidence interval, BMI body mass index, HF heart failure, EF ejection fraction, CHD coronary heart disease, HTN hypertension, COPD chronic obstructive pulmonary disease, eGFR estimated glomerular filtration rate; FIB-4 fibrosis 4 score.

*All estimates are from a multiple linear regression adjusted for all listed variables. Estimates per one unit increase unless otherwise specified.