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. 2020 Oct 30;10:18729. doi: 10.1038/s41598-020-75290-4

Table 3.

Association of HIV/HCV viral markers and medication regimens with pASP (mmHg).

β-estimate (mmHg)
[95% CI]*
p value
Variables among All HIV + 
HCV positive status 1.47 [0.26, 2.67] 0.0170
HIV viral load (10,000 copies/mL)  − 0.02 [− 0.05, 0.02] 0.3481
CD4 + T-cell count (200 cells/mm3)  − 0.68 [− 1.10, − 0.27] 0.0011
ART regimen
NRTI + PI vs. No ART 0.65 [− 1.28, 2.59] 0.5088
NRTI + NNRTI vs. No ART 0.53 [− 1.59, 2.65] 0.6258
Other ART vs. No ART  − 0.90 [− 2.59, 0.79] 0.2981
Variables among All HCV cases
HIV positive status 0.53 [− 0.99, 2.05] 0.4922
HCV viral load (10,000 copies/mL) 0.001 [− 0.0003, 0.003] 0.1084
Interferon exposure 0.70 [− 3.74, 5.13] 0.7578

HCV hepatitis C virus, PASP pulmonary artery systolic pressure, CI confidence interval, ART anti-retroviral therapy, NRTI nucleoside reverse transcriptase inhibitor, PI protease inhibitor, NNRTI non-nucleoside reverse transcriptase inhibitor.

*Adjusted for: age, sex, race/ethnicity, and heart failure.