Transporter-targeted nano-drug delivery systems for enhanced and site-specific drug delivery. GLUT1, facilitative glucose transporter-1 (SLC2A1); MCT1, monocarboxylate transporter-1 (SLC16A1); ChT, choline transporter (SLC5A7); OCTN2, novel organic cation transporter-1 or organic cation/carnitine transporter (SLC22A5); LAT1, L-amino acid transporter-1 (SLC7A5); ASCT2, Alanine-Serine-Cysteine Transporter-1 (SLC1A5); SMVT, sodium-coupled multivitamin transporter (SLC5A6); ATB0,+, amino acid transporter B0,+ (SLC6A14); PEPT1, peptide transporter (SLC15A1); ABST, apical bile salt transporter (SLC10A2).