Figure 1.
Representative 1H nuclear magnetic resonance (NMR) spectra of urine samples and discrimination between healthy control and gastric cancer groups. (A) Typical 1H NMR spectra with an internal standard signal (0.025% TSP) at 0 ppm. The left panel shows a representative 1H NMR spectrum for healthy controls, and the right panel shows a representative 1H NMR spectrum for patients with gastric cancer. (B) Orthogonal projections to the orthogonal projection for a latent structure-discriminant analysis (OPLS-DA) score plot of the healthy control and gastric cancer groups. The model was constructed with one predictive (Pp) and two orthogonal (Po) components. The overall goodness of fit and cross-validation coefficients are 86.5 and 72.8%, respectively. Black boxes: samples from healthy controls; red triangles: samples from patients with gastric cancer.