Figure 2.

Identification of contributing metabolites by statistical total correlation spectroscopy, their relative levels in urine samples, and ROC analysis. (A) The color scale P(corr)p on the right represents a modeled correlation, and Pp represents a modeled covariation. The names are indicated for metabolites with noticeable signals, whose distribution was different between the healthy control and gastric cancer groups. (B) Relative concentrations of identified metabolites in urine samples from healthy controls and patients with gastric cancer and associated p-values. The shown false discovery rate (FDR)-adjusted p-values were acquired through the online statistical analysis tool Metaboanalyst (www.metaboanalyst.ca). (C) ROC curves of each identified metabolite, with area under the curve (AUC), sensitivity, and specificity.