Table 2.
Identified metabolites, with changes in their levels in gastric cancer (GC) and receiver operating characteristic (ROC) analysis results.
| No. | Metabolites | Chemical Shift (ppm) | p-Value | Changes (GC over Controls) | ROC Analysis | ||
|---|---|---|---|---|---|---|---|
| AUC | Sensitivity (%) | Specificity (%) | |||||
| 1 | Alanine | 1.49(d), | 1.18 × 10−4 | ▲ | 0.748 | 70 | 80 |
| 2 | Citrate | 2.54(d), 2.68(d) | 1.60 × 10−4 | ▲ | 0.632 | 50 | 70 |
| 3 | Creatine | 3.04(s) | 1.90 × 10−9 | ▲ | 0.863 | 80 | 90 |
| 4 | Creatinine | 3.05(s), 4.07(s) | 3.27 × 10−5 | ▽ | 0.723 | 60 | 80 |
| 5 | Glycerol | 3.57(m), 3.66(m), 3.78(m), | 7.51 × 10−19 | ▽ | 0.936 | 90 | 90 |
| 6 | Hippurate | 3.98(d), 7.55(t), 7.64(t), 7.83(m) | 1.75 × 10−6 | ▲ | 0.74 | 70 | 70 |
| 7 | Phenylalanine | 7.32(m), 7.38(m), 7.42(m) | 1.13 × 10−8 | ▲ | 0.802 | 80 | 70 |
| 8 | Taurine | 3.27(t), 3.43(t) | 1.90 × 10−6 | ▲ | 0.759 | 80 | 70 |
| 9 | 3-hydroxybutyrate | 1.21(d) | 4.61 × 10−4 | ▽ | 0.706 | 60 | 70 |
▲ represents up-regulation and ▽ represents down-regulation.