Table 2.
Clinicopathological features of colorectal polyps according to expression of MSH2 and EPCAM.
| Colorectal Polyps | MSH2 Expression | p-Value | EPCAM Expression | p-Value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| − | + | Total | − | + | Total | |||||
| I | NI | |||||||||
| CL | FL | |||||||||
| Location | 0.178 | 0.08 | ||||||||
| Right colon | 21 | 16 | 1 | 0 | 0 | 36 | ||||
| Left colon and rectum | 17 | 8 | 1 | 4 | 0 | 20 | ||||
| Unknown | 8 | 1 | 0 | 1 | 0 | 8 | ||||
| 46 | 25 | 71 | 2 | 5 | 0 | 64 | 71 | |||
| Size (mm) | 0.020 | 0.597 | ||||||||
| ≤5 | 14 | 16 | 0 | 2 | 0 | 28 | ||||
| 6-10 | 21 | 7 | 1 | 3 | 0 | 24 | ||||
| ≥11 | 11 | 2 | 1 | 0 | 0 | 12 | ||||
| 46 | 25 | 71 | 2 | 5 | 0 | 64 | 71 | |||
| Histology | 0.018 | 0.766 | ||||||||
| TA | 25 | 10 | 1 | 2 | 0 | 32 | ||||
| TVA | 2 | 0 | 0 | 0 | 0 | 2 | ||||
| HP | 0 | 4 | 0 | 0 | 0 | 4 | ||||
| SSL | 15 | 11 | 1 | 2 | 0 | 23 | ||||
| TSA | 4 | 0 | 0 | 1 | 0 | 3 | ||||
| 46 | 25 | 71 | 2 | 5 | 0 | 64 | 71 | |||
| Dysplasia | 0.000 | 0.086 | ||||||||
| WD | 1 | 9 | 0 | 0 | 0 | 10 | ||||
| LGD | 19 | 9 | 0 | 1 | 0 | 27 | ||||
| HGD | 26 | 7 | 2 | 4 | 0 | 27 | ||||
| 46 | 25 | 71 | 2 | 5 | 0 | 64 | 71 | |||
| Mutated gene | 0.042 | 0.000 | ||||||||
| EPCAM | 13 | 2 | 1 | 4 | 0 | 10 | ||||
| EPCAM-MSH2 | 3 | 0 | 1 | 1 | 0 | 1 | ||||
| MSH2 | 30 | 23 | 0 | 0 | 0 | 53 | ||||
| 46 | 25 | 71 | 2 | 5 | 0 | 64 | 71 | |||
Abbreviations: −, negative; +, positive; I, informative; NI, noninformative; CL, complete loss; FL, focal loss; TA, tubular adenoma; TVA, tubulovillous adenoma; HP, hyperplastic polyp; SSL, sessile serrated lesion; TSA, traditional serrated adenoma; WD, without dysplasia; LGD, low-grade dysplasia; and HGD, high-grade dysplasia.