Table 3.
Clinicopathological features of precursor lesions of extra-GI origin and benign neoplasms according to the expressions of MSH2 and EPCAM.
| MSH2 Expression | p-Value | EPCAM Expression | p-Value | ||||||
|---|---|---|---|---|---|---|---|---|---|
| − | + | Total | − | + | Total | ||||
| I | NI | ||||||||
| Lesion | |||||||||
| Benign | 8 | 0 | 0 | 8 | 0 | ||||
| Precursor extra GI | 6 | 3 | 0 | 3 | 6 | ||||
| 14 | 3 | 17 | 0 | 11 | 6 | 17 | |||
| Location | 0.000 | ||||||||
| Skin | 8 | 0 | 0 | 8 | 0 | ||||
| Breast | 0 | 1 | 0 | 1 | 0 | ||||
| Cervix | 0 | 2 | 0 | 2 | 0 | ||||
| Endometrium | 6 | 0 | 0 | 0 | 6 | ||||
| 14 | 3 | 17 | 0 | 11 | 6 | 17 | |||
| Histology | 0.004 | ||||||||
| Sebaceoma | 3 | 0 | 0 | 3 | 0 | ||||
| Sebaceous adenoma | 5 | 0 | 0 | 5 | 0 | ||||
| DCIS | 0 | 1 | 0 | 1 | 0 | ||||
| HSIL | 0 | 2 | 0 | 2 | 0 | ||||
| SH | 2 | 0 | 0 | 0 | 2 | ||||
| CH | 4 | 0 | 0 | 0 | 4 | ||||
| 14 | 3 | 17 | 0 | 11 | 6 | 17 | |||
| Mutated gene | 0.22 | ||||||||
| MSH2 | 14 | 1 | 0 | 9 | 6 | ||||
| EPCAM | 0 | 2 | 0 | 2 | 0 | ||||
| 14 | 3 | 17 | 0 | 11 | 6 | 17 | |||
Abbreviations: −, negative; +, positive; I, informative; NI, noninformative; DCIS, ductal carcinoma in situ; HSIL, high squamous intraepithelial lesion; SH, simplex hyperplasia; and CH, complex hyperplasia.