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The effect of PTX resistance on PI3K/Akt and MAPK pathways. (A) The expression profiles of PI3K/AKT and (B) MAPK signaling pathway members were determined in untreated and PTX-treated PTX-res MCF-7 cells by immunoblotting assay. β-actin and GAPDH were used as loading control. Densitometry analysis was shown at Figure S1 from different batches of PTX-resistant MCF-7 cells.
