Transcript levels of potential oncogenic mediators in prostate-cancer cell lines and in human prostate-cancer tissue. Transcript levels of indicated genes measured using real-time PCR. (A) MKI67, (B) CCND1, (C) TP53, (D) HIF1A, (E) RELA, (F) BIRC5, (G) NOS2, (H) SEPP1, (I) CDKN1A, (J) CDKN1B, (K) GLUT1, (L) GLUT12. PCa: prostate cancer, HPEC: parental primary prostate cells, CWR-R1ca: xenograft PCa cells, DU145: brain metastasis PCa cells, LNCaP: lymph-node metastasis PCa cells, NCI-H660: lymph-node metastasis PCa cells, MDA-PCa-2b: bone metastasis PCa cells, PC3: bone metastasis PCa cells, nd: not detected. For human PCa samples, data shown as pooled samples: mean ± standard deviation (n = 11).