Reactive Species |
Reactive Nitrogen Species |
Unclear |
Oxidative Enzymes |
Xanthine Dehydrogenase (XDH) |
Unclear |
Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase |
Unclear |
Superoxide Dismutase (SOD) |
High risk |
Inducible Nitric Oxide Synthase (iNOS) |
High risk |
Myeloperoxidase (MPO) |
Unclear |
Antioxidative Enzymes and Transcriptional Factors |
Glutathione Peroxidase (GPx) |
Low risk |
Glutathione Reductase (GSR) |
High risk |
Catalase |
High risk |
Xanthine oxidase (XO)-Uric Acid |
Unclear |
Nuclear Factor Erythroid 2-Related Factor (Nrf2) |
Unclear |
Peroxisome proliferator-activated receptors (PPARs) |
Unclear |
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) |
Unclear |
Degradation Products and End Products |
Protein |
Protein carbonyls |
Low risk |
3-nitrotyrosin (3-NO-Tyr) |
High risk |
Protein glutathionylation |
Unclear |
Dityrosine |
Unclear |
Advanced oxidation protein products (AOPPs) |
High risk |
Advanced glycation end products (AGEs) |
High risk |
Amino acids |
Asymmetric dimethylarginine (ADMA) |
Unclear |
Lipid |
F2-isoprostane (F2-isoP) |
Low risk |
Malondialdehyde (MDA) |
Low risk |
4-hydroxynonenal (4-HNE) |
Unclear |
Hydroxyoctadecadienoic acid (HODE) |
Unclear |
Oxysterol |
Unclear |
DNA |
8-dihydro-2′deoxyguanosine (8-oxodG) |
Unclear |