Table 1.
Potency of SxIIIC across NaV channel subtypes.
| Subtype | IC50 ± SEM (nM) | n |
|---|---|---|
| NaV1.1 | 132.0 ± 11.6 | 5 |
| NaV1.2 | 363.8 ± 53.8 | 5 |
| NaV1.3 | 89.4 ± 11.1 | 3 |
| NaV1.4 | 15.11 ± 10.7 | 10 |
| NaV1.5 | >5000 | 4 |
| NaV1.6 | 124.9 ± 11.1 | 4 |
| NaV1.7 | 152.2 ± 21.8 | 4 |
| NaV1.8 | >5000 | 3 |
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