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. 2020 Sep 30;12(10):3012. doi: 10.3390/nu12103012

Figure 6.

Figure 6

Extra virgin olive oil (EVOO) extracts modulated uterine contraction-related protein expression. Mice were treated with EVOO extracts (28, 70, 140 mg/kg oral gavage) or the same volume of vehicle or ibuprofen each week before oxytocin injection. After 30 min, we collected uterine samples for the Western blot test. (a) cyclooxygenase-2 (COX2), (b) oxytocin receptor (OTR), (c) phosphor–myosin light chain 20 (p-MLC20), (d) p-ERK, (e) PKCδ, and (f) Transient receptor potential ankyrin 1 (TRPA1) protein expression. C, control; V, vehicle (oxytocin-induced) P, ibuprofen 120 mg/kg. * p < 0.05; ** p < 0.01; *** p < 0.001 compared with C group. # p < 0.05; ## p < 0.01; ### p < 0.001 compared with V group. OTR: ERK: extracellular signal-regulated kinase, MLC20: myosin light chain 20, PKCδ: protein kinase C-δ.