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. 2020 Oct 7;13(10):295. doi: 10.3390/ph13100295

Figure 2.

Figure 2

Effect of the combination of lutein/zeaxanthin, curcumin, and vitamin D (LCD) on tear volume, tear breakup time (TBUT) scoring, Fluorescein staining scoring, Rose Bengal staining scoring and evaluation of inflammation in benzalkonium chloride (BAC)-induced dry eye syndrome in rats (n = 7 per group). Control: No treatment; Dry Eye: BAC-induced dry eye syndrome; LCD I; Dry Eye + LCD I: BAC-induced dry eye syndrome plus LCD I (100 mg/kg body weight); Dry Eye + LCD II: BAC-induced dry eye syndrome plus LCD II (200 mg/kg body weight). Data are presented as a bar with means and standard deviations. (ANOVA and Tukey′s post-hoc test. Statistical significance between groups is shown by: * p < 0.05; ** p < 0.01; **** p < 0.0001 compared as control group; # p < 0.01; ### p < 0.001; #### p < 0.0001 compared as Dry Eye group; $$ p < 0.01 compared as Dry Eye + LCD I group).