Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 7;13(10):295. doi: 10.3390/ph13100295

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Effect of the combination of lutein/zeaxanthin, curcumin and vit D (LCD) on NF-κB, TNF-α, IL-1 β, IL-6, and IL-8 protein levels in benzalkonium chloride (BAC)-induced dry eye syndrome in rats (n = 7 per group). Control: No treatment; Dry Eye: BAC-induced dry eye syndrome; LCD I; Dry Eye + LCD I: BAC-induced dry eye syndrome plus LCD I (100 mg/kg body weight); Dry Eye + LCD II: BAC-induced dry eye syndrome plus LCD II (200 mg/kg body weight). Data are expressed as % of the control value. Western blot analysis (n = 3 at least) was performed with actin included to ensure equal protein loading. (ANOVA and Tukey′s post-hoc test. Statistical significance between groups is shown by: * p < 0.05; *** p < 0.001; **** p < 0.0001 compared as control group; ^## p < 0.01; ^### p < 0.001; ^#### p < 0.0001 compared as Dry Eye group; ^$ p < 0.05; ^$$$$ p < 0.0001 compared as Dry Eye + LCD I group).

Effect of the combination of lutein/zeaxanthin, curcumin and vit D (LCD) on NF-κB, TNF-α, IL-1 β, IL-6, and IL-8 protein levels in benzalkonium chloride (BAC)-induced dry eye syndrome in rats (n = 7 per group). Control: No treatment; Dry Eye: BAC-induced dry eye syndrome; LCD I; Dry Eye + LCD I: BAC-induced dry eye syndrome plus LCD I (100 mg/kg body weight); Dry Eye + LCD II: BAC-induced dry eye syndrome plus LCD II (200 mg/kg body weight). Data are expressed as % of the control value. Western blot analysis (n = 3 at least) was performed with actin included to ensure equal protein loading. (ANOVA and Tukey′s post-hoc test. Statistical significance between groups is shown by: * p < 0.05; *** p < 0.001; **** p < 0.0001 compared as control group; ^## p < 0.01; ^### p < 0.001; ^#### p < 0.0001 compared as Dry Eye group; ^$ p < 0.05; ^$$$$ p < 0.0001 compared as Dry Eye + LCD I group).