Table 1.
Dataset characteristics.
| Dataset Characteristics | ||||||
|---|---|---|---|---|---|---|
| Variable and its description | BZ n = 107 (35%) |
TS n = 125 (41%) |
I/IL n = 74 (24%) |
Total n = 306 (100%) |
||
| Geographical characteristics | ||||||
| Altitude of residence | Mean in meter (range) |
884 (214–2153) |
53 (0–253) |
699 (564–1513) |
p < 0.0001 † | 279 (0–2153) |
| Demographic characteristics | ||||||
| Gender | Male | 59 of 107 (55%) |
66 of 125 (52.8%) |
41 of 74 (55.4%) |
p = 0.9 ‡ | 166 of 306 (54%) |
| Female | 48 of 107 (45%) |
59 of 125 (47.2%) |
33 of 74 (44.6%) |
140 of 306 (46%) |
||
| Mean age | Year (range) |
67 (19–101) |
69 (16–98) |
70 (21–100) |
p = 0.5 † | 69 (16–101) |
| Pathological characteristics | ||||||
| Localization § | Head&Neck&face a | 25 of 107 (23.4%) |
29 of 125 (23.2%) |
18 of 74 (24.3%) |
p = 0.9 ‡ | 72 of 306 (23.5%) |
| Trunk b | 35 of 107 (32.7%) |
41 of 125 (32.8%) |
25 of 74 (33.8%) |
101 of 306 (33%) |
||
| Upper Limb c | 16 of 107 (15%) |
16 of 125 (12.8%) |
12 of 74 (16.2%) |
44 of 306 (14.4%) |
||
| Lower Limb d | 30 of 107 (28%) |
35 of 125 (28%) |
18 of 74 (24.3%) |
83 of 306 (27.1%) |
||
| Other sites e | 1 of 107 (0.9%) |
4 of 125 (3.2%) |
1 of 74 (1.4%) |
6 of 306 (2%) |
||
| Stage | I B | 10 of 107 (9.3%) |
9 of 125 (7.2%) |
12 of 74 (16.2%) |
p = 0.003 ‡ | 31 of 306 (10%). |
| II | 68 of 107 (63.6%) |
89 of 125 (71.2 %) |
34 of 74 (45.9%) |
191 of 306 (62%) |
||
| III | 21 of 107 (19.6%) |
25 of 125 (20%) |
9 of 74 (12.2%) |
55 of 306 (18%) |
||
| IV | 6 of 107 (5.6%) |
2 of 125 (1.6%) |
9 of 74 (12.2%) |
17 of 306 (6%) |
||
| unknown | 2 of 107 (1.9%) |
0 of 125 (0%) |
10 of 74 (13.5%) |
12 of 306 (4%) |
||
| Lymph nodes | Positive | 23 of 107 (21.5%) |
22 of 125 (17.6%) |
13 of 74 (17.6%) |
p = 0.7 ‡ | 58 of 306 (19%) |
| Negative | 82 of 107 (76.6%) |
103 of 125 (82.4%) |
51 of 74 (68.9%) |
236 of 306 (77%) |
||
| unknown | 2 of 107 (1.9%) |
0 of 125 (0%) |
10 of 74 (13.5%) |
12 of 306 (4%) |
||
| Breslow’s thickness | Mean in mm (range) |
4.5 (1.8−27.6) |
4.6 (1.8−30) |
4.6 (1.8−30) |
p = 0.9 † | 4.6 mm (1.8−30) |
| Ulceration status | yes | 52 of 107 (48.6%) |
65 of 125 (52%) |
23 of 74 (31%) |
p = 0.3 ‡ | 140 of 306 (46%) |
| no | 54 of 107 (50.5%) |
57 of 125 (45.6%) |
34 of 74 (46%) |
145 of 306 (47%) |
||
| unknown | 1 of 107 (0.9%) |
3 of 125 (2.4%) |
17 of 74 (23%) |
21 of 306 (7%) |
||
| Histotype ¶ | NOS f | 2 of 107 (1.9%) |
46 of 125 (36.8%) |
37 of 74 (50%) |
p < 0.0001 ‡ | 85 of 306 (27.7%) |
| Nodular g | 57 of 107 (53.3%) |
61 of 125 (48.8%) |
22 of 74 (29.7%) |
140 of 306 (46%) |
||
| Superficial spreading h | 32 of 107 (29.9%) |
1 of 125 (0.8%) |
7 of 74 (9.5%) |
40 of 306 (13%) |
||
| Acral i | 5 of 107 (4.7%) |
0 of 125 (0%) |
3 of 74 (4.1%) |
8 of 306 (3%) |
||
| Others l, m, n, o, p, q, r | 10 of 107 (9.3%) |
17 of 125 (13.6%) |
5 of 74 (6.8%) |
32 of 306 (10%) |
||
| Unknown | 1 of 107 (0.9%) |
0 of 125 (0%) |
0 of 74 (0%) |
1 of 306 (0.3%) |
||
† Ordinary one-way ANOVA test (the unknown cases were excluded from the analysis); ‡ Chi-square test (the unknown cases were excluded from the analysis); underlined p highlights statistically significant results by univariate analysis (p < 0.05). § ICD-O code was used to define anatomical tumor localization: a. C44.0; C44.1; C44.2; C44.3; C44.4; b. C44.5; c. C44.6; d. C44.7 and e. C51.0; ¶ SNOMED code was used to define tumor histotypes: f. not specified; g. M87213; h. M87433; i. M87443; l. M87453; m. M87723; n. M87733; o. M87803; p. M87303; q. M87423; r. M87713.