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Mutational characteristics of the whole dataset.
| Mutation Status | n = 288 | (100%) |
|---|---|---|
| BRAF a | n = 96 | (33.3%) |
| NRAS b | n = 62 | (21.5%) |
| Focal positivity for NRAS b c | n = 5 | (1.8%) |
| BRAF and NRAS negative | n = 124 | (43%) |
| Positive IHC for BRAF and NRAS | n = 1 | (0.4%) |
a: BRAF mutations V600E or V600K; b: NRAS mutations Q61R or K or L or H; c: one sample is defined with focal positivity (−/+) by IHC and four both through IHC and ddPCR (0.08 or 0.16 copies/μL).
