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. 2020 Oct 12;9(10):977. doi: 10.3390/antiox9100977

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of geraniol pretreatment (100 or 200 mg/kg) on the Keap1/Nrf2/HO-1 pathway in the ISO-induced rat MI model. Gene expression was assessed by determination of the mRNA levels of (a) Keap 1, (b) Nrf2 and (c) HO-1. Protein expression was assessed by determination of the protein levels of (d) Keap 1, (e) nuclear Nrf2 and (f) HO-1 via Western blot analysis. ISO: isoproterenol. All values were stated as mean ± SD (n = 6). €, p < 0.05 compared to the normal group; ҂, p < 0.05 compared to the ISO-induced MI group; *, p < 0.05 compared to the ISO + geraniol (100 mg/kg) group. Comparisons done using one-way ANOVA followed by Tukey-Kramer post-hoc test.