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Inhibitory signaling is diminished in melanoma responders, whereas BCC responders experience increased inhibitory signaling. (A,E) Probability of signaling and averaged expression of the ligand/receptor/downstream target in each cell population for melanoma (A) and BCC (E). (B–D) Signaling of the Fc fragment of IgG receptor IIb (FCGR2B) (B), interleukin 6 (IL6) (C), PD1 (D) pathways for melanoma. (F–H) Signaling of the FCGR2B (F), IL6 (G), PD1 (H) pathways for BCC.
