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Cox analysis of overall survival in CN-AML training cohort (n = 162) according to DNA repair score, and NPM1/FLT3 mutational status. Hazard ratio (HR) and p-values are shown for each parameter in univariate and multivariate Cox analysis. ITD: internal tandem duplication.
| Scores | Univariate Cox Analysis | Multivariate Cox Analysis | ||
|---|---|---|---|---|
| HR | p-Value | HR | p-Value | |
| DNA repair score | 2.76 | 1.49 × 10−8 | 2.66 | 5.1 × 10−8 |
| NPM1 mutation/FLT3-ITD classification | 1.81 | 1.18 × 10−4 | 1.76 | 6.2 × 10−4 |
