Table 1.
Demographic and clinico-pathologic characteristics of the oropharyngeal squamous cell carcinomas (OPSCC) of the study population overall and according to the period of diagnosis.
| Overall | 2010–2014 | 2015–2019 | p Value 1 | |
|---|---|---|---|---|
| Median age, years (IQR) | 61 (54–68) | 62 (55–69) | 61 (54–68) | 0.51 |
| Mean age, years (range) | 62 (28–90) | 62 (37–84) | 61 (28–90) | 0.37 |
| Sex distribution, n (%) | 0.054 | |||
| Men | 264 (77.9) | 121 (82.9) | 143 (74.1) | |
| Women | 75 (22.1) | 25 (17.1) | 50 (25.9) | |
| Total | 339 (100) | 146 (100) | 193 (100) | |
| Smoking status | 0.76 | |||
| never | 63 (22.9) | 23 (22.3) | 40 (23.3) | |
| former | 55 (20.0) | 23 (22.3) | 32 (18.6) | |
| current | 157 (57.1) | 57 (55.4) | 100 (58.1) | |
| Total | 275 (100) | 103 (100) | 172 (100) | |
| Cancer subsite, n (%) | 0.22 | |||
| Tonsils | 155 (45.7) | 66 (45.2) | 89 (46.1) | |
| Base of the tongue | 133 (39.2) | 63 (43.2) | 70 (36.3) | |
| Other2 | 51 (15.1) | 17 (11.6) | 34 (17.6) | |
| Total | 339 (100) | 146 (100) | 193 (100) | |
| T status, n (%) | 0.07 | |||
| T1-T2 | 160 (52.6) | 71 (59.2) | 89 (48.4) | |
| T3-T4 | 144 (47.4) | 49 (40.8) | 95 (51.6) | |
| Total | 304 (100) | 120 (100) | 184 (100) | |
| N status, n (%) | 0.58 | |||
| N0 | 71 (23.4) | 30 (25.0) | 41 (22.3) | |
| N+ | 233 (76.6) | 90 (75.0) | 143 (77.7) | |
| Total | 304 (100) | 120 (100) | 184 (100) |
1 For the comparison between the two periods. 2 Soft palate, uvula, epiglottic vallecula, amygdaloglossus sulcus, posterior wall.