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. 2020 Sep 30;12(10):3001. doi: 10.3390/nu12103001
Key Term/Abbreviation Definition
(I, II, III, IV, V) Complexes I-V of the mitochondrial respiratory chain
1,25-dihydroxyvitamin D 1,25(OH)2D
2′-PP 2′-Phosphophloretin
2,3-BPG 2,3-Bisphosphoglycerate
AD Autosomal dominant
AKT Protein kinase B
Alp Alkaline phosphatase
AMP Adenosine monophosphate
AMPK AMP-activated protein kinase
AR Autosomal recessive
ATP Adenosine triphosphate
BBMV Brush border membrane vesicle
BPG Bisphosphoglycerate
CASR Calcium-sensing receptor
CKD Chronic kidney disease
c-myb V-myb avian myeloblastosis viral oncogene homolog
CrP Creatine phosphate
CYP24A1 The vitamin D 24-hydroxylase
CYP27B1 The vitamin D 1-α hydroxylase
DMP1 Dentin matrix acidic phosphoprotein 1
DNA Deoxyribonucleic acid
EGF Epidermal growth factor
EGR1 Early growth response 1
Enpp1 Ectonucleotide pyrophosphatase-phosphodiesterase family member 1
ER Endoplasmic reticulum
ERK1 Extracellular signal-regulated kinase 1
ERK2 Extracellular signal-regulated kinase 2
Etv5 ETS variant 5
FADH Flavin adenine dinucleotide
FAM20c Golgi-associated secretory pathway kinase
FAP Fluorapatite mineral
FGF Fibroblast growth factor
FGF23 Fibroblast growth factor 23
FGFR1 Fibroblast growth factor receptor 1
FGFR1c FGFR1 isoform c
FRS2 FGFR substrate 2
GALNT3 Polypeptide
N-Acetylgalactosaminyltransferase 3
GC Glucocorticoid
GCMB Glial cell missing gene
GI Gastrointestinal
GNAS Guanine nucleotide-binding protein, alpha stimulating
GRB2 Growth factor receptor bound protein 2
HVDDR Hereditary 1,25(OH)2D-resistant rickets
IBGC Idiopathic basal ganglia calcification
IC Intracellular
ICF Intracellular fluid
IU International units
IP6K1 Inositol hexakisphosphate kinase 1
IP6K2 Inositol hexakisphosphate kinase 2
IP6 Inositol hexakisphosphate
IP7 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate
IP8 1,5-bisdiphosphoinositol 1,2,3,4-tetrakisphosphate
IV Intravenous
JAM2 Junctional adhesion molecule 2
KL α-Klotho
Km Michaelis-Menten affinity constant
LOF Loss of function
LVH Left ventricular hypertrophy
MAPK Mitogen-activated protein kinase
MAPK1 Mitogen-activated protein kinase 1
MAPK3 Mitogen-activated protein kinase 3
MEPE Matrix extracellular phosphoglycoprotein
mPTP Mitochondrial permeability transition pore
MV Matrix vesicle
MYORG Myogenesis regulating glycosidase
Na+ Sodium ion
NAD Nicotinamide adenine dinucleotide
NADH Reduced nicotinamide adenine dinucleotide
NADPH Reduced nicotinamide adenine dinucleotide phosphate
NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells
NHE3 Sodium/hydrogen exchanger isoform 3
NHERF-1 Na+/H+ exchanger regulatory factor
NOS Nitric oxide synthase
NPT1 Sodium-dependent phosphate transport protein 1
NPT2a Sodium-dependent phosphate transport protein 2a
NPT2b Sodium-dependent phosphate transport protein 2b
NPT2c Sodium-dependent phosphate transport protein 2c
NVU Neurovascular unit
OPG Osteoprotegerin
OPN Osteopontin
P10 Postnatal day 10
PDGFB Platelet-derived growth factor subunit B
PDGFRB Platelet-derived growth factor receptor beta
PFA Phosphonoformate/phosphonoformic acid
PFBC Primary familial brain calcification
Phex Phosphate-regulating endopeptidase homolog, X-linked
PHOSPHO1 Phosphoethanolamine/phosphocholine phosphatase 1
Pi Inorganic phosphate
PIC Mitochondrial phosphate carrier
PIT1 Type III sodium-dependent phosphate transporter 1
PIT2 Type III sodium-dependent phosphate transporter 2
PKA Protein kinase A
PKC Protein kinase C
PLCγ Phospholipase C gamma isoform.
PPi Pyrophosphate
PPIs Proton pump inhibitors
PTH Parathyroid hormone
PTHR1 Parathyroid hormone 1 receptor
RANK Receptor activator of NF-κB
RANKL Receptor activator of NF-κB ligand
RDA Recommended daily allowance
RNA Ribonucleic acid
ROS Reactive oxygen species
RXR Retinoic acid X-receptor
SAMD9 Sterile alpha motif domain containing 9
SIBLING Small integrin-binding ligand, N-linked glycoprotein
SLC17 Solute carrier family 17
SLC20A1 Solute carrier family 20 member 1; gene encoding PIT1
SLC20A2 Solute carrier family 20 member 2; gene encoding PIT2
SLC25A3 Solute carrier family 25 member 3; gene encoding PIC
SLC34A1 Solute carrier family 34 member 3; gene encoding NPT2a
SLC34A2 Solute carrier family 34 member 2; gene encoding NPT2b
SLC34A3 Solute carrier family 34 member 3; gene encoding NPT2c
SM Standard medium
SOS Son of sevenless
SPX A protein domain named after SYG1/Pho81/XPR1 proteins
TEER Transepithelial electrical resistance
TNAP Tissue non-specific alkaline phosphatase
TNFRSF11B TNF receptor superfamily member 11B
VATP ATP flux
VDR Vitamin D receptor
VRE Vitamin D-reponsive elements
VSMC Vascular smooth muscle cell
WNT Wingless-related integration site
WT Wild-type
XLH X-linked hyperphosphatemia
XPR1 Xenotropic and polytropic retrovirus receptor 1