Key Term/Abbreviation | Definition |
(I, II, III, IV, V) | Complexes I-V of the mitochondrial respiratory chain |
1,25-dihydroxyvitamin D | 1,25(OH)2D |
2′-PP | 2′-Phosphophloretin |
2,3-BPG | 2,3-Bisphosphoglycerate |
AD | Autosomal dominant |
AKT | Protein kinase B |
Alp | Alkaline phosphatase |
AMP | Adenosine monophosphate |
AMPK | AMP-activated protein kinase |
AR | Autosomal recessive |
ATP | Adenosine triphosphate |
BBMV | Brush border membrane vesicle |
BPG | Bisphosphoglycerate |
CASR | Calcium-sensing receptor |
CKD | Chronic kidney disease |
c-myb | V-myb avian myeloblastosis viral oncogene homolog |
CrP | Creatine phosphate |
CYP24A1 | The vitamin D 24-hydroxylase |
CYP27B1 | The vitamin D 1-α hydroxylase |
DMP1 | Dentin matrix acidic phosphoprotein 1 |
DNA | Deoxyribonucleic acid |
EGF | Epidermal growth factor |
EGR1 | Early growth response 1 |
Enpp1 | Ectonucleotide pyrophosphatase-phosphodiesterase family member 1 |
ER | Endoplasmic reticulum |
ERK1 | Extracellular signal-regulated kinase 1 |
ERK2 | Extracellular signal-regulated kinase 2 |
Etv5 | ETS variant 5 |
FADH | Flavin adenine dinucleotide |
FAM20c | Golgi-associated secretory pathway kinase |
FAP | Fluorapatite mineral |
FGF | Fibroblast growth factor |
FGF23 | Fibroblast growth factor 23 |
FGFR1 | Fibroblast growth factor receptor 1 |
FGFR1c | FGFR1 isoform c |
FRS2 | FGFR substrate 2 |
GALNT3 | Polypeptide N-Acetylgalactosaminyltransferase 3 |
GC | Glucocorticoid |
GCMB | Glial cell missing gene |
GI | Gastrointestinal |
GNAS | Guanine nucleotide-binding protein, alpha stimulating |
GRB2 | Growth factor receptor bound protein 2 |
HVDDR | Hereditary 1,25(OH)2D-resistant rickets |
IBGC | Idiopathic basal ganglia calcification |
IC | Intracellular |
ICF | Intracellular fluid |
IU | International units |
IP6K1 | Inositol hexakisphosphate kinase 1 |
IP6K2 | Inositol hexakisphosphate kinase 2 |
IP6 | Inositol hexakisphosphate |
IP7 | 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate |
IP8 | 1,5-bisdiphosphoinositol 1,2,3,4-tetrakisphosphate |
IV | Intravenous |
JAM2 | Junctional adhesion molecule 2 |
KL | α-Klotho |
Km | Michaelis-Menten affinity constant |
LOF | Loss of function |
LVH | Left ventricular hypertrophy |
MAPK | Mitogen-activated protein kinase |
MAPK1 | Mitogen-activated protein kinase 1 |
MAPK3 | Mitogen-activated protein kinase 3 |
MEPE | Matrix extracellular phosphoglycoprotein |
mPTP | Mitochondrial permeability transition pore |
MV | Matrix vesicle |
MYORG | Myogenesis regulating glycosidase |
Na+ | Sodium ion |
NAD | Nicotinamide adenine dinucleotide |
NADH | Reduced nicotinamide adenine dinucleotide |
NADPH | Reduced nicotinamide adenine dinucleotide phosphate |
NF-κB | Nuclear factor kappa-light-chain-enhancer of activated B cells |
NHE3 | Sodium/hydrogen exchanger isoform 3 |
NHERF-1 | Na+/H+ exchanger regulatory factor |
NOS | Nitric oxide synthase |
NPT1 | Sodium-dependent phosphate transport protein 1 |
NPT2a | Sodium-dependent phosphate transport protein 2a |
NPT2b | Sodium-dependent phosphate transport protein 2b |
NPT2c | Sodium-dependent phosphate transport protein 2c |
NVU | Neurovascular unit |
OPG | Osteoprotegerin |
OPN | Osteopontin |
P10 | Postnatal day 10 |
PDGFB | Platelet-derived growth factor subunit B |
PDGFRB | Platelet-derived growth factor receptor beta |
PFA | Phosphonoformate/phosphonoformic acid |
PFBC | Primary familial brain calcification |
Phex | Phosphate-regulating endopeptidase homolog, X-linked |
PHOSPHO1 | Phosphoethanolamine/phosphocholine phosphatase 1 |
Pi | Inorganic phosphate |
PIC | Mitochondrial phosphate carrier |
PIT1 | Type III sodium-dependent phosphate transporter 1 |
PIT2 | Type III sodium-dependent phosphate transporter 2 |
PKA | Protein kinase A |
PKC | Protein kinase C |
PLCγ | Phospholipase C gamma isoform. |
PPi | Pyrophosphate |
PPIs | Proton pump inhibitors |
PTH | Parathyroid hormone |
PTHR1 | Parathyroid hormone 1 receptor |
RANK | Receptor activator of NF-κB |
RANKL | Receptor activator of NF-κB ligand |
RDA | Recommended daily allowance |
RNA | Ribonucleic acid |
ROS | Reactive oxygen species |
RXR | Retinoic acid X-receptor |
SAMD9 | Sterile alpha motif domain containing 9 |
SIBLING | Small integrin-binding ligand, N-linked glycoprotein |
SLC17 | Solute carrier family 17 |
SLC20A1 | Solute carrier family 20 member 1; gene encoding PIT1 |
SLC20A2 | Solute carrier family 20 member 2; gene encoding PIT2 |
SLC25A3 | Solute carrier family 25 member 3; gene encoding PIC |
SLC34A1 | Solute carrier family 34 member 3; gene encoding NPT2a |
SLC34A2 | Solute carrier family 34 member 2; gene encoding NPT2b |
SLC34A3 | Solute carrier family 34 member 3; gene encoding NPT2c |
SM | Standard medium |
SOS | Son of sevenless |
SPX | A protein domain named after SYG1/Pho81/XPR1 proteins |
TEER | Transepithelial electrical resistance |
TNAP | Tissue non-specific alkaline phosphatase |
TNFRSF11B | TNF receptor superfamily member 11B |
VATP | ATP flux |
VDR | Vitamin D receptor |
VRE | Vitamin D-reponsive elements |
VSMC | Vascular smooth muscle cell |
WNT | Wingless-related integration site |
WT | Wild-type |
XLH | X-linked hyperphosphatemia |
XPR1 | Xenotropic and polytropic retrovirus receptor 1 |