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. 2020 Oct 2;9(10):2232. doi: 10.3390/cells9102232

Figure 8.

Figure 8

Reduction in the slow/oxidative markers is accompanied by increased expression of proNGF/p75NTR axis in Tibialis anterior (TA) lysates. (A) Western blot and densitometric analysis of CREB phosphorylation at Ser133 and of AMPK phosphorylation at Thr172 in three month-old wild-type (WT, N = 3) and mdx mice (N = 6). (B) Western blot and densitometric analysis of PGC-1α, COXIV and cytochrome C from three month-old WT (N = 6) and mdx mice (N = 6). (C) Immunoblot and densitometric analysis of p75NTR in TA from three month-old WT (N = 3) and mdx mice (N = 4). (D) Immunoblot and densitometric analysis of proNGF in TA from three month-old WT (N = 3) and mdx mice (N = 4). Tubulin and vinculin served as the loading control. Data are expressed as the mean ± SD. Statistical analysis was performed by using the Student’s t test. * p < 0.05; † p < 0.01. Arbitrary units (a.u.).