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Influence of 5′-guanosine number on RNA structure. Capped RNAs containing two or three 5′-guanosines (left) adopt a monomeric structure that exposes the cap and enables RNA processing and metabolism, whereas those with a single capped G (right) adopt a cap-sequestered conformation that promotes dimerization and packaging (Cap = red sphere, guanosines = green spheres). Adapted from [75], with permission.
