Table 2.
Ciclosporin, tacrolimus, and diltiazem prescribing measures stratified by electronic health record (EHR) system along with odds ratios (ORs) from a univariable and multivariable logistic regression model.
| Medicine and EHR systems | Breaches of safety guidance (%), mean | Univariable logistic regression, OR (95% CI) | Mixed-effects logistic regressiona, OR (95% CI) | |
| Diltiazem |
|
|
|
|
|
|
EMIS | 22.7 | Reference | Reference |
|
|
Microtest | 1.0 | 0.045 (0.039-0.052) | 0.051 (0.044-0.060) |
|
|
SystmOne | 7.0 | 0.252 (0.249-0.254) | 0.239 (0.235-0.243) |
|
|
Vision | 12.0 | 0.462 (0.451-0.473) | 0.300 (0.290-0.309) |
| Ciclosporin and tacrolimus |
|
|
|
|
|
|
EMIS | 23.2 | Reference | Reference |
|
|
Microtest | 6.1 | 0.103 (0.072-0.148) | 0.161 (0.107-0.242) |
|
|
SystmOne | 7.8 | 0.238 (0.230-0.247) | 0.271 (0.256-0.287) |
|
|
Vision | 10.8 | 0.378 (0.346-0.412) | 0.219 (0.195-0.247) |
aAdjusted for clinical commissioning group (CCG) membership as a random effect, percentage of patients over 65 years of age, percentage of patients under 18 years of age, percentage of patients with a long-term health condition, dispensing practice status, single-handed practice status, ruralness or urbanness of location, and index of multiple deprivation.