Table 1.

Salient features of each domain according to each level of CDS.

Feature	CDSa level
	Population	Encounter	Precision
Alert timing	Asynchronous	Synchronous	Both
Data timing	Cumulative	At time of encounter	Preemptive
Basis	Evidence-based	Evidence-based	Individualized
Strategies	Dashboards, iterative risk scores, work lists	Interruptive alerts, risk scores, care pathways, passive alerts	Either population- or encounter-based
Clinical examples	Diabetic foot exam, HIV drug efficacy, annual cholesterol	Heart failure guidelines, QT-prolonging drugs, performance metrics, deterioration index	Telemonitoring and mobile health, CYP2D6/opiate metabolism, polygenic risk scores, BRCA cancer screening

^aCDS: clinical decision support.