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. 2020 Oct 10;9(10):3239. doi: 10.3390/jcm9103239

Figure 2.

Figure 2

Comparison of clinical characteristics among the low (L)-insulin-like gwowth factor 1 (IGF-1), intermediate (I)-IGF-1, and high (H)-IGF-1 groups. (A) Skeletal muscle mass index (SMI) values were significantly lower in the L-IGF-1 group than in the H-IGF-1 group. (B) Handgrip strength values were significantly lower in the L-IGF-1 group than in the H-IGF-1 group. (C) The L-IGF-1 group significantly showed the highest prevalence of sarcopenia (p < 0.001 by the chi-squared test), whereas the H-IGF-1 group significantly had the lowest prevalence of sarcopenia (p < 0.001 by the chi-squared test). The prevalence of sarcopenia significantly increased stepwise with a reduction in the IGF-1 level (p < 0.001 by the Cochran–Armitage trend test). (D) The H-IGF-1 group significantly had the lowest prevalence of slow gait speed (p = 0.003 by the chi-squared test). The prevalence of slow gait speed significantly increased stepwise with a reduction in the IGF-1 level (p = 0.003 by the Cochran–Armitage trend test). C-A, Cochran–Armitage trend test; C-S, chi-squared test.