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Biogenesis of extracellular vesicle (EV) subtypes, termed exosomes, microvesicles and apoptotic bodies. Exosomes are intraluminal vesicles which are released when a multivesicular body fuses with the cell membrane through exocytosis. Microvesicles are formed by outward shedding of the cell membrane into extracellular space. Apoptotic bodies are generated when cells undergo apoptosis. Figure was generated with BioRender.
