Table 4.
Physical activity according to the GPAQ and muscular test in the intention-to-treat population.
| Baseline (T0) | End of CT (T1) | End of RT (T2) | 1 Year after Inclusion (T3) (n = 113; n = 97) | LMM Coefficients 1 (95% CI) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (158/168) | (n = 139; n = 129) | (n = 134; n = 128) | |||||||||||
| Mean | SD | Mean | SD | p | Mean | SD | p | Mean | SD | p | |||
| Total MET (MET.min/wk) | Control | 1998.63 | 2632.06 | 2339.37 | 4181.16 | 0.03 | 1522.69 | 1591.27 | 0.048 | 2157.1 | 2902.02 | 0.03 | β1 = 0.74 [0.37; 1.10], p < 0.001 |
| APAD | 2133.07 | 3206.8 | 2023.1 | 1729.05 | 1760.78 | 1464.05 | 2363.96 | 2386.1 | β0 = −0.005 [−0.007; 0.007], p = 0.864 | ||||
| Recreational–Moderate intensity (MET.min/wk) | Control | 338 | 511.97 | 299.08 | 539.7 | <0.001 | 395.82 | 538.71 | 0.001 | 506.27 | 728.95 | 0.349 | β1 = 0.95 [0.46; 1.43], p < 0.001 |
| APAD | 296.98 | 454.64 | 632.87 | 730.3 | 600.56 | 630.25 | 537.2 | 694.62 | β0 = 0.021 [0.012; 0.030], p < 0.001 | ||||
| Recreational–Vigorous intensity (MET.min/wk) | Control | 122.78 | 461.56 | 219.86 | 829.16 | 0.433 | 173.73 | 618.49 | 0.636 | 216.28 | 777.94 | 0.353 | β1 = 0.27 [−0.13; 0.67], p = 0.184 |
| APAD | 135 | 450.99 | 187.6 | 538.19 | 220.31 | 767.45 | 274.06 | 654.44 | β0 = 0.008 [0.001; 0.015], p = 0.019 | ||||
| Work—Moderate intensity (MET.min/wk) | Control | 816.46 | 1479.06 | 515.11 | 1419.7 | 0.006 | 429.28 | 849.11 | 0.674 | 667.65 | 1423.57 | 0.743 | β1 = 0.34 [−0.19; 0.86], p = 0.212 |
| APAD | 824.4 | 1638.35 | 576.59 | 1001.46 | 508.78 | 998.82 | 546.1 | 963.79 | β0 = −0.012 [0.022; −0.002], p = 0.014 | ||||
| Work—Vigorous intensity (MET.min/wk) | Control | 212.41 | 1378.38 | 523.17 | 2778.69 | 0.935 | 53.73 | 316.49 | 0.813 | 120.35 | 804.99 | 0.721 | β1 = 0.10 [−0.16; 0.36], p = 0.454 |
| APAD | 374.29 | 1906.61 | 78.76 | 420.47 | 79.38 | 556.03 | 225.15 | 1119.72 | β0 = 0.00003 [−0.005; 0.005], p = 0.989 | ||||
| Travel—Moderate intensity (MET.min/wk) | Control | 508.99 | 816.59 | 782.16 | 1117.32 | 0.071 | 470.12 | 702.81 | 0.277 | 646.55 | 1307.34 | 0.141 | β1 = 0.19 [−0.35; 0.72], p = 0.494 |
| APAD | 502.4 | 805.68 | 547.29 | 964.76 | 465.23 | 542.61 | 781.44 | 1734.93 | β0 = 0.01 [0.01; 0.02], p = 0.022 | ||||
| Sitting or reclining time (min/day) | Control | 372.41 | 175.26 | 355.29 | 197.46 | 0.041 | 357.07 | 171.3 | 0.84 | 337.12 | 164.13 | 0.946 | β1 = 0.18 [0.02; 0.33], p = 0.023 |
| APAD | 400.85 | 178.62 | 391.05 | 177.33 | 369.2 | 177.26 | 353.76 | 183.5 | β0 = −0.004 [−0.008; −0.0004], p = 0.029 | ||||
| Muscular test | |||||||||||||
| Sit-to-stand 30 s | Control | 18.09 | 4.67 | 17.3 | 5.51 | 0.013 | 18.86 | 5.32 | 0.39 | 19.42 | 6.02 | 0.615 | β1 = 0.001 [−0.002; 0.002], p = 0.094 |
| β0 = 0.001 [0.0002; 0.002], p = 0.017 | |||||||||||||
| APAD | 17.72 | 4.87 | 18.61 | 4.77 | 19.68 | 5.64 | 20.04 | 6.16 | |||||
| Sit-to-stand ratio | Control | 1.97 | 0.38 | 1.93 | 0.2 | 0.341 | 1.94 | 0.16 | 0.59 | 1.93 | 0.16 | 0.844 | β1 = −0.002 [−0.014; 0.01], p = 0.694 |
| (30 s/15 s) | β0 = −0.0001 [−0.0004; 0.0002], p = 0.431 | ||||||||||||
| APAD | 1.93 | 0.18 | 1.94 | 0.17 | 1.95 | 0.13 | 1.93 | 0.15 | |||||
1 In the linear mixed model (LMM; log transformed variables): β1 is the coefficient of the variable ‘arm’ (interpreted as APAD effect with respect to Control) noted as β2 when interaction arm by time was significant. β0 is the coefficient of the variable time (weeks) variable. Note: No baseline imbalance was observed for the studied variables (for sitting or reclining time (GPAQ), p = 0.136). CT: chemotherapy, RT: radiotherapy.