Table 6.
Dietary intake per day (3-day record) and weight control variables in the intention-to-treat population.
| Baseline (T0) | End of Radiotherapy (T2) | 1 Year after Inclusion (T3) | LMM Coefficients 1 [95% CI] | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SD | p | Mean | SD | p | Mean | SD | p | |||
| Total energy (Kcal) | Control | 1507.46 | 362.87 | 0.312 | 1402.41 | 386.27 | 0.637 | 1382.97 | 384.02 | 0.16 | β1 = −0.0020 [−0.054; 0.050], p = 0.947 |
| APAD | 1463.76 | 434.09 | 1377.56 | 373.81 | 1452.03 | 372.93 | β0 = −0.0010 [−0.002; −0.0002], p = 0.013 | ||||
| Animal proteins (g) | Control | 19.64 | 17.92 | 0.233 | 10.38 | 10.04 | 0.003 | 8.35 | 8.99 | 0.233 | β1 = −0.26 [−0.55; 0.017], p = 0.066 |
| APAD | 17.29 | 17.03 | 7.95 | 9.94 | 7.42 | 8.55 | β0 = −0.017 [−0.022; −0.011], p < 0.001 | ||||
| Vegetal proteins (g) | Control | 8.85 | 5.93 | 1 | 5.61 | 4.29 | 0.415 | 5.49 | 4.3 | 0.836 | β1 = −0.084 [−0.23; 0.067], p = 0.276 |
| APAD | 9.2 | 6.87 | 5.45 | 5.59 | 5.53 | 5.07 | β0 = −0.010 [−0.013; −0.007], p < 0.01 | ||||
| Lipids (g) | Control | 61.43 | 21.98 | 0.147 | 57 | 22.9 | 0.22 | 54.82 | 24.05 | 0.407 | β1 = −0.037 [−0.11; 0.034], p = 0.306 |
| APAD | 57.72 | 23.49 | 52.32 | 18.73 | 56.34 | 19.54 | β0 = −0.001 [−0.003; −0.0002], p = 0.021 | ||||
| Monounsaturated lipids (g) | Control | 22 | 9.64 | 0.207 | 19.39 | 9.95 | 0.805 | 19.73 | 12.88 | 0.538 | β1 = −0.024 [−0.11; 0.057], p = 0.558 |
| APAD | 20.55 | 9.27 | 18.37 | 7.15 | 19.62 | 7.51 | β0 = −0.002 [−0.003; 0.0004], p = 0.009 | ||||
| Polyunsaturated lipids (g) | Control | 7.86 | 5.35 | 0.549 | 7.92 | 5.32 | 0.791 | 7.26 | 4.51 | 0.085 | β1 = 0.022 [−0.078; 0.12], p = 0.671 |
| APAD | 7.4 | 4.31 | 7.35 | 3.97 | 8.11 | 4.42 | β0 = 0.0002 [−0.001; 0.002], p = 0.773 | ||||
| Simple sugars (g) | Control | 69.97 | 28.08 | 0.926 | 61.93 | 23.26 | 0.273 | 61.26 | 24.46 | 0.504 | β1 = 0.023 [−0.058; 0.10], p = 0.582 |
| APAD | 70.25 | 30.15 | 65.66 | 24.96 | 64.03 | 26.17 | β0 = −0.002 [−0.004; 0.001], p < 0.001 | ||||
| Alcohol (g) | Control | 4.18 | 6.58 | 0.742 | 4.11 | 5.95 | 0.019 | 4.15 | 6.83 | 0.055 | β1 = −0.091 [−0.010; −0.0009], p = 0.549 |
| APAD | 4.44 | 7.31 | 2.25 | 4.18 | 2.98 | 5.67 | β0 = −0.005 [−0.010; -0.0009], p = 0.020 | ||||
| Fiber (g) | Control | 15.54 | 5.56 | 0.277 | 15.35 | 5.73 | 0.02 | 15.35 | 6.03 | 0.003 | β1 = 0.096 [0.026; 0.17], p = 0.007 |
| APAD | 16.28 | 5.87 | 17.37 | 6.49 | 17.58 | 5.9 | β0 = 0.0005 [−0.0006; 0.001], p = 0.389 | ||||
| Weight control | |||||||||||
| Weight (kg) | Control | 67 | 14.13 | 0.44 | 66.23 | 12.93 | 0.571 | 67.13 | 13.98 | 0.576 | β1 = 0.020 [−0.020; 0.060], p = 0.334 |
| APAD | 68.41 | 14.6 | 67.57 | 13.56 | 68.28 | 14.19 | β0 = 0.0001 [−0.0001; 0.0002], p = 0.389 | ||||
| BMI (kg/m2) | Control | 25.22 | 5.3 | 0.317 | 24.95 | 5.01 | 0.51 | 25.23 | 5.28 | 0.655 | β1 = 0.020 [−0.019; 0.059], p = 0.320 |
| APAD | 25.72 | 5.14 | 25.29 | 4.79 | 25.47 | 5.01 | β0 = 0.0001 [−0.0001; 0.0002], p = 0.337 | ||||
| Waist size (cm) | Control | 163.08 | 6.49 | 0.717 | 87.09 | 13.05 | 0.827 | 87.26 | 15.74 | 0.344 | β1 = 0.0034 [−0.027; 0.034], p = 0.827 |
| APAD | 163.06 | 6.32 | 86.87 | 11.72 | 88.65 | 13.48 | β0 = 0.0002 [−0.0001; 0.0004], p = 0.133 | ||||
1 In the linear mixed model (LMM; log transformed variables): β1 is the coefficient of the variable ‘arm’ (interpreted as APAD effect with respect to Control) noted as β2 when interaction arm by time was significant. β0 is the coefficient of the variable time (weeks) variable. Note: No baseline imbalance was observed for the studied variables.