. 2020 Oct 7;9(10):2241. doi: 10.3390/cells9102241

Table 1.

General Characteristics of the included studies.

Author	Type of Study	Country	n patient	n Teeth	Groups of Study	n per Group	Tooth	Etiology of Pulpal Necrosis	Follow-up Time in Months
ElSheshtawy et al. 2020 [29]	RCT, Parallel	Egypt	26	26	A. PRP	11	Incisor	Secondary to trauma and dens invaginatus	12
ElSheshtawy et al. 2020 [29]	RCT, Parallel	Egypt	26	26	B. BC	11	Incisor	Secondary to trauma and dens invaginatus	12
Mittal et al. 2019 [30]	RCT, Parallel	India	16	16	A. PRF	4	Incisor	Secondary to trauma/caries	12
Mittal et al. 2019 [30]	RCT, Parallel	India	16	16	B. BC	4	Incisor	Secondary to trauma/caries	12
Ragab et al. 2019 [31]	RCT, Parallel	Egypt	22	22	A. PRF	11	Incisor	Secondary to trauma	12
Ragab et al. 2019 [31]	RCT, Parallel	Egypt	22	22	B. BC	11	Incisor	Secondary to trauma	12
Ulusoy et al. 2019 [32]	RCT, Parallel	Turkey	77	77	A. PRP	18	Incisor	Secondary to trauma	Until complete healing 10–49
					B. PRF	17
					C. PP	17
					D. BC	21
Rizk et al. 2019 [33]	RCT, Parallel	Egypt	26	26	A. PRP	13	Incisor	Secondary to trauma	12
Rizk et al. 2019 [33]	RCT, Parallel	Egypt	26	26	B. PRF	12	Incisor	Secondary to trauma	12
Shivashankar et al. 2017 [34]	RCT, Parallel	India	60	60	A. PRF	20	Incisor	Secondary to trauma/caries	12
					B. BC	15
					C. PRP	19
Alagl et al. 2017 [35]	RCT, Split Mouth	Saudi Arabia	16	32	A. PRP	15	Incisor and premolars	Secondary to trauma/caries	12
Alagl et al. 2017 [35]	RCT, Split Mouth	Saudi Arabia	16	32	B. BC	15	Incisor and premolars	Secondary to trauma/caries	12
Bezgin et al. 2015 [36]	RCT, Parallel	Turkey	20	22	A. PRP	11	Incisor and premolars	Secondary to trauma/caries	18
Bezgin et al. 2015 [36]	RCT, Parallel	Turkey	20	22	B. BC	11	Incisor and premolars	Secondary to trauma/caries	18
Narang et al. 2015 [37]	RCT, Parallel	India	20	20	A. MTA	5	NR	Secondary to trauma/caries	18
					B. BC	5
					C. PRF	5
					D. PRP	5
Jadhav et al. 2012 [38]	RCT, Parallel	India	20	20	A. PRP	10	Incisor	Secondary to trauma/caries	12
Jadhav et al. 2012 [38]	RCT, Parallel	India	20	20	B. BC	10	Incisor	Secondary to trauma/caries	12

Legend: RCT: randomized clinical trial; PRP: platelet-rich plasma; BC: induced blot clot; PRF: platelet-rich fibrin; PP: platelet pellet; MTA: mineral trioxide aggregate.