PEG	Polyethylene Glycol
SELEX	Systemic Evolution of Ligands by Exponential enrichment
KD	Dissociation Constant
SOMAmer	Slow off-rate modified aptamer
WHO	World Health Organization
BBB	Blood–brain barrier
tFNA	Tetrahedral framework nucleic acid
GTG	Gint4.TtFNA-GMT8
TMZ	Temozolomide
PLGA-b-PEG	Poly(lactic-co-glycolic)-block-Poly Ethylene Glycol
GBM	Glioblastoma
siRNA	Small interfering RNA
PDGFβ	Platelet-derived growth factor β
OPN	Osteopontin
EGFR	Epidermal growth factor receptor
EDB	Extra-domain B
VEGF	Vascular endothelial growth factor
HH	Hedgehog
PTCH1	Patched1
SMO	Smoothened
IDH1	Isocitrate dehydrogenase
SOX2	SRY (sex determining region Y)-box 2