Figure 4.
rp1l1 is required for the normal photoreceptor physiological response in aged animals. (A) Sample traces from a 12-month-old wild-type and rp1l1 mutant fish. (B) b-wave amplitude for wild-type and rp1l1 mutants. The rp1l1 mutant zebrafish have a significantly decreased b-wave amplitude under all light intensities. (C) b-wave implicit time for the wild-type and mutant zebrafish. The mutants have a significantly faster b-wave under the 0.2 cd·s/m2 intensity. The box and whisker plots depict medians and distributions, with all animals plotted. n = 7 for wild-type; n = 8 for mutants. * p < 0.05.