Figure S4.

Effects of cold exposure and pro-inflammatory conditions on BAT from the WT and SIRT1^Tg+mice. (A and B) mRNA levels in BAT (n = 4–10 mice/group). (C) Relative BAT and iWAT weight in the mice (n = 19–21 mice/group). Bars represent mean ± SEM. In panels A and B, statistical analysis was performed with two-way ANOVA. ∗Comparison between the mice with the same genotype with or without cold exposure (panel A) or treated with LPS or not (panel B). In panel C, statistical analysis was conducted with the Mann–Whitney U test. ^∗Comparison between genotypes. ^∗p < 0.05 and ^∗∗p < 0.01.