NMF	Non-negative Matrix Factorization
LDA	latent Dirichlet allocation
PLDA	Parallelized latent Dirichlet allocation
PCA	principal component analysis
t-SNE	t-distributed Stochastic Neighbor Embedding
SBS	Single Base Substitution
PCAWG	Pan Cancer Analysis of Whole Genomes
RR	Reconstruction Rate
CNS	Central Nervous System
HCC	Hepatocellular Carcinoma
Oligo	Oligodendroglioma
AdenoCa	Adeno Carcinoma