WHO |
World Health Organization |
GC-MS |
Gas Chromatography Mass Spectrometry |
HPLC |
High-performance liquid chromatography |
TLC |
Thin-Layer Chromatography |
LC-MS |
Liquid Chromatography–Mass Spectrometry |
ROS |
Reactive Oxygen Species |
IL |
Interleukin |
TNF |
Tumor Necrosis Factor |
LPS |
Lipopolysaccharide |
NOS |
Nitric Oxide Synthase |
COX-2 |
Cyclooxygenase 2 |
NO |
Nitric Oxide |
PGE-2 |
Prostaglandin E2 |
NF-κB |
Nuclear Factor kappa B |
AP-1 |
Activator Protein 1 |
JNK |
c-Jun N-terminal Kinase |
MAPK |
Mitogen-Activated Protein Kinase |
FXR |
Farnesoid X Receptor |
Nrf2 |
Nuclear Factor Erythroid 2-related Factor 2 |
D-GaIN |
D-galactosamine |
AchE |
Acetylcholinesterase |
MAO |
Monoamine oxidase |
5-HT |
Serotonin |
NMDA |
N-Methyl-D-aspartate |
GABA |
γ-aminobutyric Acid |
GAD |
Generalized Anxiety Disorder |
SSRI |
Selective Serotonin Reuptake Inhibitor |
NNK |
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone |
B[a]P |
Benzo[a]pyrene |
DHM |
Dihydromethysticin |
DHK |
Dihydrokavain |
AhR |
Aryl Hydrocarbon Receptor |
NNAL |
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol |
CYP2A5 |
Cytochrome P450 2A5 |
UCC |
Urothelial cell carcinoma |
TRAMP |
Transgenic Adenocarcinoma of Mouse Prostate |
Skp2 |
S phase Kinase-associated Protein 2 |
NECa |
Neuroendocrine Carcinomas |
AR |
Androgen Receptor |
NSCLC |
Non-Small Cell Lung Cancer |
UCK2 |
Uridine-Cytidine Kinase 2 |
XIAP |
X-Linked Inhibitor of Apoptosis |
FDA |
Food and Drug Administration |
ALT |
Alanine Transaminase |
AST |
Aspartate transaminase |
GGT |
Gamma-glutamyltransferase |
NTP |
National Toxicology Program |
BZD |
Benzodiazepine |
CIOMS |
Council for International Organizations of Medical Sciences |
ALP |
Alkaline phosphatase |
CAERS |
CFSAN Adverse Event Reporting System |
ADME |
Absorption, distribution, metabolism, and excretion |
CFSAN |
Center for Food Safety and Applied Nutrition |
QC |
Quality control |