Skip to main content
. 2020 Sep 25;12(10):2761. doi: 10.3390/cancers12102761

Table 1.

Features predicting malignant transformation of choroidal nevus into melanoma are listed in the mnemonic ”TFSOM UHHD ‘to find small ocular melanoma using helpful hints daily’”. The percentages of choroidal nevus growth into melanoma based on number of involved features are reported along with recommended clinical monitoring [20,21].

Mnemonic Feature N of Features Choroidal Nevus Growth into Melanoma (%) Monitoring
To Find Small Ocular Melanoma Using helpful Hints Daily Thickness > 2 mm None 4% Every 6 months Inline graphic Once a year (if stability persists)
Fluid (subretinal)
Symptoms
 - decreased vision
 - flashes/floaters
1 Feature 36% Every 4–6 months
Orange pigment
Margin ≤ 3 mm to disc 2 Features 45% Every 4–6 months
Ultrasonographic hollowness
Halo absence
Drusen absence
3 or more Features 50% Referral to Experienced Center
    Inline graphic
Primary treatment  Prognosis