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. 2020 Oct 3;9(10):2236. doi: 10.3390/cells9102236

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Microalbuminuria and TIF in diabetic mice. (A) Urinary albumin-to-creatinine ratio (ACR) from 24 h urine. Each point on the graph represents an individual mouse (n = 9/5/8/6). The significance, shown in the table (graph insert) was assessed using two-way ANOVA with sex (male or female) and diabetes (non-diabetic or diabetic) as the two factors. Sex, Diabetes: main effect of sex/diabetes, respectively. Sex*Diabetes: interaction (determines whether the one main effect depends on the level of the other main effect). (B) Fibronectin. Representative images of fibronectin immunohistochemistry (magnification: 100×). (C) Collagen I. Representative images of collagen type I immunohistochemistry (magnification: 100×). *** P ≤ 0.001.