Table 8.
Top 20 significantly differentially expressed genes between asthmatic horses in exacerbation and healthy horses according to the Padjusted. The normalized mean expression values calculated by DESeq2, the log2 fold change, as well as the adjusted p-values are listed.
| Gene Name | Normalized Mean Expression Value | Log2 Fold Change | Padjusted |
|---|---|---|---|
| HSPB7 | 374 | 2.60 | 3.26 × 10−7 |
| LOC100056936 | 814 | 4.33 | 2.53 × 10−6 |
| LOC100056698 | 1050 | 3.71 | 3.65 × 10−6 |
| GSTA1 | 321 | 5.73 | 4.41 × 10−6 |
| CXCL6 | 840 | 5.23 | 6.63 × 10−6 |
| PMEPA1 | 1042 | 0.81 | 7.73 × 10−6 |
| S100A12 | 2715 | 4.09 | 4.58 × 10−5 |
| IGFBP3 | 1063 | 4.02 | 7.04 × 10−5 |
| LOC100630497 | 73 | −1.39 | 9.63 × 10−5 |
| CADM3 | 297 | 4.04 | 1.18 × 10−4 |
| AP2A1 | 1463 | 0.38 | 1.46 × 10−4 |
| SAA1 | 2773 | 2.70 | 1.46 × 10−4 |
| SCN1B | 106 | 1.64 | 1.46 × 10−4 |
| S100G | 41 | −1.71 | 3.00 × 10−4 |
| LOC111768320 | 74 | 1.42 | 3.06 × 10−4 |
| PTPRQ | 30 | −2.58 | 3.27 × 10−4 |
| LOC111773141 | 10 | 2.63 | 5.07 × 10−4 |
| PCDH15 | 35 | 2.64 | 5.07 × 10−4 |
| IL1R2 | 159 | 3.68 | 5.76 × 10−4 |