Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
JNK’s scaffold protein JIP-1. JIP-1 is a crucial regulator of the JNK signaling pathway. It links multiple MAPK members, tethering them together and accelerating the reaction cascade. JIP-1 regulates signal transduction and helps localize pathway in components of the cell such as the plasma membrane, the cytoplasm, the nucleus, the Golgi and in neurons in the pre- and post-synaptic elements.
