Table 1.
Molecular characterization of Clostridium perfringens isolated from 2003 to 2018. The strains were classified based on toxinotype, geographical origin, and presence of further non-typing toxin genes.
| No. of Isolates (Intra-Class %) | ||||||
|---|---|---|---|---|---|---|
| Type | Further Toxin Genes | Geographical Origin | Total | Overall Total | ||
| Umbria Region | Other Regions | Unknown | ||||
| A | none | 237 (63.7) | 122 (55.7) | 24 (58.5) | 383 (60.6) | 588 (93.0) |
| cons-cpb2 | 72 (19.4) | 37 (16.9) | 11 (26.8) | 120 (19.0) | ||
| aty-cpb2 | 41 (11.0) | 40 (18.2) | 4(9.8) | 85 (13.4) | ||
| B | aty-cpb2 | - | 1 (0.5) | - | 1 (0.2) | 1 (0.2) |
| C | none | 4 (1.1) | 2 (0.9) | - | 6 (0.9) | 7 (1.1) |
| cons-cpb2 | 1 (0.3) | - | - | 1 (0.2) | ||
| D | none | 2 (0.5) | 3 (1.4) | - | 5 (0.8) | 19 (3.0) |
| cpe | 6 (1.6) | 1 (0.5) | 2 (4.9) | 9 (1.4) | ||
| cpe + aty-cpb2 | 2 (0.5) | 1 (0.5) | - | 3 (0.5) | ||
| aty-cpb2 | 1 (0.3) | 1 (0.5) | - | 2 (0.3) | ||
| E | cpe + aty-cpb2 | 1(0.3) | - | - | 1 (0.2) | 1 (0.2) |
| F * | none | 5 (1.3) | 8 (3.7) | - | 13 (2.0) | 16 (2.5) |
| cons-cpb2 | - | 1 (0.5) | - | 1 (0.2) | ||
| aty-cpb2 | - | 2 (0.9) | - | 2 (0.3) | ||
| Total | 372 (100) | 219 (100) | 41 (100) | 632 (100) | 632 (100) | |
* The presence of the cpe gene is considered included in the definition toxinotype F because the CPE toxin is typing in this case; “-“ no isolates.