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Ca2+-signaling pathways and hepatocellular carcinoma (HCC) cell proliferation; (A) Schematic representation of pathways involved in Ca2+-signaling in HCC cells leading to enhanced cell proliferation; (B) schematic representation of the roles of increased [Ca2+]cyt in activation of the PI3kinase/Akt/mTORC and ERK pathways in mediating enhanced cell proliferation.
