Table 3.
Association analysis between venous thrombotic events and principal demographic, clinical characteristics and comorbidities. Parametric data were represented as mean (standard deviation) and non-parametric data as median <1st, 3rd interquartile>.
| Venous Thrombosis Positive (21 Patients) |
Venous Thrombosis Negative (53 Patients) |
ODD Ratio | p-Value | |
|---|---|---|---|---|
| Gender, n (%) | ||||
| Male | 15 (71.4%) | 29 (54.7%) | 2.07 <0.71–5.98> | 0.197 |
| Female | 6 (28.6%) | 24 (45.3%) | ||
| Age, (years) | 66.7 (±16.78) | 69.40 (±14.54) | - | 0.529 |
| Comorbidities, n (%) | ||||
| AF | 0 (0%) | 3 (5.7%) | - | 0.266 |
| CRF | 2 (9.5%) | 3 (5.7%) | 1.75 <0.32–9.65> | 0.551 |
| Obesity | 1 (4.8%) | 6 (11.3%) | 0.39 <0.06–2.49> | 0.385 |
| DM | 5 (23.8%) | 11 (20.7%) | 1.19 <0.37–3.82> | 0.774 |
| Cardiovascular disease | 8 (38.1%) | 24 (45.3%) | 0.74 <0.27–2.04> | 0.574 |
| COPD | 2 (9.5%) | 6 (11.3%) | 0.82 <0.17–3.89> | 0.822 |
| Asthma | 0 (0%) | 0 (0%) | - | - |
| Cancer | 1 (4.8%) | 9 (16.9%) | 0.24 <0.4–1.48> | 0.166 |
| PaO2/FiO2 | 204 <180–236> | 235 <184–281> | - | 0.280 |
| Patients underwent positive pressure respiratory assistance, n (%) | 19 (90.5%) | 34 (64.1%) | 5.31 <1.27–22.16> | 0.024 |
| Patients allocation, n (%) | ||||
| ICU | 12 (57.1%) | 6 (11.3%) | 10.44 <3.22–33.86> | <0.0001 |
| General ward | 9 (42.8%) | 47 (88.7%) | ||
| Laboratory tests results | ||||
| LDH, (U/L) | 779 <631–867> | 481 <359–697> | - | 0.001 |
| Ferritin, (mcg/L) | 1379 <644.4–1590> | 623.7 <356.5–1093> | - | 0.333 |
| CRP, (mg/dl) | 13.78 <4.2–21.6> | 1.56 <0.54–6.53> | - | 0.001 |
| Lymphocytes, (×10/mcL3) | 0.74 (±0.14) | 0.82 (±0.29) | - | 0.371 |
| Coagulation test results | ||||
| Fibrinogen, (mg/dL) | 645 <421.5–795.5> | 505 <413–633.5> | - | 0.352 |
| D-dimer, (mcg/mL) | 2.78 <1.42–5.73> | 1.08 <0.45–1.59> | - | <0.0001 |
| aPTT, (s) | 44.72 (±15.92) | 42.12 (±9.8) | - | 0.458 |
| PT, (s) | 15.3 (±2.6) | 14.3 (±2.6) | - | 0.158 |
| PLTS, (×103/mcL) | 299.6 (±145.3) | 254.3 (±116.3) | - | 0.171 |
| Hospital LOS, (days) | 45.7 (±15.3) | 29 (±19.5) | - | 0.152 |
| Mortality | 3 (14.3%) | 9 (16.9%) | 0.81 <0.21–3.11> | 0.777 |
Legend: AF, atrial fibrillation; CRF, chronic renal failure; DM, diabetes mellitus; COPD, chronic obstructive pulmonary disease; ICU, intensive care unit; LDH, lactic dehydrogenase; CRP, C-reactive protein; LOS length of stay; Italics: Distinguish subgroups; Bold: Highlight statistically significant results.