Table 2.
Risk of clinical outcomes in patients with the lowest quartile (Quartile 1) of the SI compared with upper quartiles (Quartile 2–4) of the SI.
| Clinical Outcomes | Total (N = 1086) |
SI Q1 (N = 273) |
SI Q2–4 (N = 813) |
Unadjusted HR (95% CI) |
p Value | Adjusted HR *(95% CI) | p Value |
|---|---|---|---|---|---|---|---|
| MACE | 154 (14.2%) | 63 (23.1%) | 91 (11.2%) | 2.23 (1.62–3.07) | <0.001 | 2.18 (1.55–3.06) | <0.001 |
| All-cause death | 81 (7.5%) | 43 (15.8%) | 38 (4.7%) | 3.60 (2.33–5.57) | <0.001 | 3.48 (2.17–5.58) | <0.001 |
| Cardiovascular death | 43 (4.0%) | 23 (8.4%) | 20 (2.5%) | 3.64 (2.00–6.63) | <0.001 | 3.02 (1.61–5.68) | 0.001 |
| Non-cardiovascular death | 38 (3.5%) | 20 (7.3%) | 18 (2.2%) | 3.55 (1.88–6.71) | <0.001 | 3.69 (1.89–7.23) | <0.001 |
| MI | 15 (1.4%) | 4 (1.5%) | 11 (1.4%) | 1.15 (0.37–3.61) | 0.81 | 1.16 (0.35-3.81) | 0.81 |
| Target lesion revascularization | 128 (11.8%) | 29 (10.6%) | 99 (12.2%) | 0.91 (0.60–1.38) | 0.67 | 0.96 (0.63–1.46) | 0.96 |
| All bleeding | 25 (2.3%) | 7 (2.6%) | 18 (2.2%) | 1.22 (0.51–2.92) | 0.66 | 0.97 (0.37–2.55) | 0.97 |
SI = sarcopenia index; Q = quartile; MACE = major adverse cardiovascular event; MI = myocardial infarction. * The following patient risk factors were included in the multivariate-adjusted Cox proportional hazard regression model: age, sex, body mass index, diabetes mellitus, hypertension, peripheral vascular disease, previous MI or PCI, current smoking, previous congestive heart failure, clinical diagnosis, diseased vessel extent and total stent length.