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. 2020 Oct 13;10(10):156. doi: 10.3390/bs10100156

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of pedunculopontine nucleus (PPN) neurotoxic lesion on the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) mRNA expression in nigral tissue. (A) Comparison between experimental groups 24 h, 48 h and 7 days after PPN lesion (F_(6,29) = 39.08 p < 0.001). The first bar (white bar) represents the non-operated group. Asterisks correspond to statistical differences between PPN lesion and both control groups (non-operated and sham operated). (B) Agarose/ethidium bromide gel electrophoresis bands representative of the semi-quantitative RT-PCR study for Nrf2 mRNA expression. One-way ANOVA test. ** p < 0.01; *** p < 0.001.