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. 2020 Sep 28;12(10):619. doi: 10.3390/toxins12100619

Table 1.

The overview of mycotoxins.

Mycotoxin Toxic Effects IARC Classification Health Guidance Value References
AFB1, AFM1 carcinogenic Group 1 As low as reasonably achievable (ALARA principle) [5,6]
OTA nephrotoxic, teratogenic, immunotoxic, neurotoxic Group 2B TWI = 120 ng/kg bw/w
PTWI = 100 ng/kg bw/w
[5,6]
FB1 hepatotoxicity, nephrotoxicity Group 2B PMTDI (FB1+FB2 +FB 3) = 2 μg/kg bw/d
TDI (FB1+FB2 +FB3) = 2 μg/kg bw/d
[1,5,6]
DON immunotoxic Group 3 TDI = 1 μg/kg bw/d [5,6,7,8]
ZEN reproductive toxicity Group 3 PMTDI = 0.5 μg/kg bw/d
TDI = 0.25 μg/kg bw/d
[5,6]
PAT hepatotoxicity Group 3 PMTDI = 0.4 μg/kg bw/d [1,5,9]
NIV immunotoxicity, hematotoxicity, myelotoxicity Group 3 TDI = 1.2 μg/kg bw/d [2,5,10]
T-2, HT-2 toxic on the skin and mucous membranes Group 3 PMTDI (T-2+HT-2) = 0.06 μg/kg bw/d
TDI (T-2+HT-2) = 0.1 μg/kg bw/d
[5]

Group 1, carcinogenic to humans; Group 2A, probably carcinogenic to humans; Group 2B, possibly carcinogenic to humans; Group 3, not classifiable as to its carcinogenicity to humans.