Table 2.
Demographic and clinical characteristics of MS patients according to SNP rs244072 group.
| CT/CC n = 92 (16.4%) |
TT n = 469 (83.6%) |
p Value | ||
|---|---|---|---|---|
| Sex, F | N (%) | 59 (64.1) | 314 (67) | 0.60 |
| Age, years | Mean, (SD) | 38.03 (11.99) | 36.09 (11.01) | 0.213 |
| MS phenotype | RR/CIS/RIS, n (%) | 85 (92.4) | 427 (91) | 0.676 |
| SP/PP, n (%) | 7 (7.6) | 42 (9) | ||
| Disease duration, months | Median (IQR) | 10.4 (1.62–48.17) | 7.9 (1.42–49.70) | 0.930 |
| EDSS | Median (IQR) | 2 (1–3) | 1.5 (1–2.5) | 0.011 |
| Clinical activity at LP | N (%) | 34 (37) | 181 (38.6) | 0.768 |
| Radiological activity at LP | N (%) | 42 (45.7) | 196 (41.8) | 0.493 |
Subjects carrying C allele of SNP rs244072 (CT/CC), TT homozygous subjects for SNP rs244072 (TT). Abbreviations: multiple sclerosis (MS), relapsing-remitting (RR), clinically isolated syndrome (CIS), secondary-progressive (SP), primary-progressive (PP), expanded disability status scale (EDSS), interquartile range (IQR), lumbar puncture (LP).