Figure 1.

Heatmap with the pseudo-color scale underneath of the differentially expressed miRNAs between complete responder (CR) (blue bar) and partial responder and progressive diseases (PRPD) (orange bar). Unsupervised hierarchical clustering was used to order samples and miRNAs, the log2-transformed microarray signal was considered. The sample tree with optimized leaf-ordering was drawn using Euclidean distances and average linkages for cluster-to-cluster distance. CR = complete responder, PRPD = partial responder and progressive diseases.