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. 2020 Sep 25;12(10):920. doi: 10.3390/pharmaceutics12100920
%EE Percent entrapment efficiency
ANOVA One-way analysis of variance
BBD Box–Behnken design
CH Chitosan
CH-NPs Chitosan NPs
CMA Critical material attributes
CPP Critical process parameters
CQA Critical quality attributes
DOE Design of experiments
E. Entamoeba
FFD Fractional factorial design
GI Gastrointestinal
ICH International Council for Harmonization
Met Metronidazole
MetNp Met containing NPs
MetNp Cap Eudragit coated capsule containing MetNp
MTP1 Metal tolerance proteins-1
NPs Nanoparticles
PNP Purine nucleoside phosphorylase
PS Particle size
QbD Quality by design
QTPP Quality target product profile
R2adj Adjusted coefficient of determination
RDC Residual drug content
RSM Response surface methodology
Sc Surface area of the uncoated capsule
SCF Simulated colonic fluid
SGF Simulated GI fluid
SGIF Simulated gastric and intestinal fluid
SIF Simulated intestinal fluid
SOD Superoxide dismutase
TPP Tripolyphosphate
Trx Thioredoxin
TrxR Thioredoxin reductase
ρo Bulk density
ρt Tapped density
Wc Weight of uncoated capsule
Wec Weight of enteric-coated capsule